Development and validation of a prediction model for bothersome stress urinary incontinence after prolapse surgery: a retrospective cohort study
【Abstract】
Objective To develop and validate a prediction model for bothersome stress urinary incontinence after prolapse surgery and to compare it to an existing clinical prediction model (CUPIDO model). Design Retrospective cohort study Setting Two tertiary hospitals in South Korea Population A total of 1,142 patients who underwent prolapse surgery with or without a concomitant midurethral sling. Methods To construct a prediction model, we performed logistic regression using both exhaustive and stepwise variable selection, and the model was both internally and externally validated. Main outcome measures Bothersome stress urinary incontinence defined as the presence of bothersome symptoms of stress urinary incontinence and/or subsequent continence procedure one year after surgery. Results Postoperative bothersome stress urinary incontinence occurred in 10% of patients. A model containing six predictors (age, diabetes mellitus, subjective urinary incontinence, prolapse reduction stress test result, type of prolapse surgery, and a concomitant midurethral sling) showed excellent performance for predicting bothersome stress urinary incontinence (area under the curve 0.74, 95% confidence interval 0.62-0.86) and outperformed the CUPIDO model (area under the curve 0.63, 95% confidence interval 0.49-0.76; DeLong’s test p= 0.014). Conclusions This prediction model might be a useful tool to guide patient decision making regarding a concomitant continence procedure at the time of prolapse surgery. The predictive value of this model needs to be validated further in cohorts with different characteristics.
【Author】
Sumin Oh, Sungyoung Lee, Woo Yeon Hwang, Dong Hoon Suh, Myung Jae Jeon
【Keywords】
Prediction model, prolapse surgery, stress urinary incontinence 
【Journal】
BJOG: An International Journal of Obstetrics and Gynaecology(IF：1) Time：2021-12-05
