What do we know about the antibody responses to SARS-CoV-2?
【Abstract】
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide causing a pandemic with millions of infected people and deaths. Currently, the scientific community is working hard to develop a specific vaccine or treatment. However, since antibody production is an important part of the adaptive immune response, to develop vaccines and therapies, we must understand the antibody response to SARS-CoV-2 infection. In this work, we summarize the most important findings of antibody-mediated immunity against SARS-CoV-2 and highlight its role in the efficient use of plasma from convalescent patients and the direct application of antibodies as treatment.
【Author】
FranciscoAlejandro Lagunas-Rangela, VeniceChávez-Valenciab
【Keywords】
COVID-19, humoral response, seroconversion, convalescent plasma
【Journal】
Immunobiology(IF:2.8) Time:2021-01-24